KETAMINE & CHRONIC PAIN
Fibromyalgia & Migraines
Hope for Treatment Resistant Chronic Pain
Administering in low doses, Ketamine has anti-inflammatory effects and is effective in tempering the production of different pro inflammatory mediators. Ketamine produces strong analgesia effects, primarily by inhibiting the N-methyl-D-aspartate receptor. A number of studies indicate that IV ketamine provides significant pain-relieving benefits in patients with refractory chronic pain. In many ways, Ketamine has the ability to “reboot the nervous system” by halting the progression of pain sensitivity and even reversing it in some cases. Additionally, unlike opioids, ketamine does not cause physical addiction.
Ever since Ketamine was first discovered in the 1960s, we have known that it has numerous ways by which it impacts pain. Ketamine works by blocking N-methyl-D-aspartate (NMDA) receptors, proteins in nerve cells that play a role in sensitizing the nervous system. Ketamine is also believed to reverse central sensitization and enhance descending modulatory pathways
How does Ketamine work for Chronic Pain?
Scientists have been using different research studies to examine how Ketamine actually works on pain pathways.
Ketamine works in multiple ways to decrease one of your own existing brain chemicals, called neurotransmitters.
These neurotransmitters are decreased at pain receptors in the brain and spinal cord.
Additionally, Ketamine works on your own natural opioid receptors to increase pain threshold thereby decreasing the amount of pain felt.
Finally, Ketamine also impacts the nerve cells of your own pain inhibiting pathways that help you cope with pain.