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Fibromyalgia & Migraines

Hope for Treatment Resistant Chronic Pain

Administering in low doses, Ketamine has anti-inflammatory effects and is effective in tempering the production of different pro inflammatory mediators. Ketamine produces strong analgesia effects, primarily by inhibiting the N-methyl-D-aspartate receptor. A number of studies indicate that IV ketamine provides significant pain-relieving benefits in patients with refractory chronic pain. In many ways, Ketamine has the ability to “reboot the nervous system” by halting the progression of pain sensitivity and even reversing it in some cases. Additionally, unlike opioids, ketamine does not cause physical addiction.

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Ever since Ketamine was first discovered in the 1960s, we have known that it has numerous ways by which it impacts pain. Ketamine works by blocking N-methyl-D-aspartate (NMDA) receptors, proteins in nerve cells that play a role in sensitizing the nervous system. Ketamine is also believed to reverse central sensitization and enhance descending modulatory pathways

How does Ketamine work for Chronic Pain?​

Scientists have been using different research studies to examine how Ketamine actually works on pain pathways.

  • Ketamine works in multiple ways to decrease one of your own existing brain chemicals, called neurotransmitters. 

  • These neurotransmitters are decreased at pain receptors in the brain and spinal cord.

  • Additionally, Ketamine works on your own natural opioid receptors to increase pain threshold thereby decreasing the amount of pain felt.

  • Finally, Ketamine also impacts the nerve cells of your own pain inhibiting pathways that help you cope with pain.

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What to Expect From Treatments



The treatments include 2 to 4 hour sessions and can be spread over a few days.



In general, patients feel effects within the first day or so and are recommended to continue their regular care.



The pain regimen is very individualized to the patient.

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Avesta Ketamine and Wellness Located in McLean, VA & Chevy Chase, MD

Avesta Ketamine and Wellness McLean
6861 Elm St, Suite 3E McLean VA 22101​


Avesta Ketamine and Wellness Chevy Chase

5454 Wisconsin Ave., Suite 1675, Chevy Chase, MD 20815 (inside APMI Wellness Center)
New Chevy Chase Patients check-in at the main front office located in Suite 1600 (same floor)

703-201-7767 |​

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