There have been numerous studies on the positive effect of Ketamine on depression and suicide, so much so that the FDA has approved a sister compound, Esketamine for treatment of depression.​

How does Ketamine work for Depression?​

Scientists have investigated the mechanism of action of Ketamine on the brain, and what we know so far is fascinating! 

  • Ketamine increases one of your own existing brain chemicals, called neurotransmitters. 

  • The name of the transmitter is Glutamate and it is one that excites nerve cells at very specific receptors, which are the sites where the neurotransmitter work.

  • This increase in the chemical occurs in pyramidal cells of the brain that are impacted by depression


What to expect from the treatments?

  • The treatments include 6 one 45-60 minute sessions spread over a 2-3 week period.

  • Research has shown this regimen to be most effective.

  • In general, patients feel effects within the first 4 treatments, and are recommended to continue their regular care with a mental health practitioner, as well as their current drug regimen.

  • The response to Ketamine is very individual with some patients feeling the effects right away, while others require all six, and occasionally more treatments.

We will assess your response at treatment 3-4 to determine how you are responding and how we can optimize the dosing to suit your response.

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Avesta Ketamine and Wellness

5454 Wisconsin Ave., Suite #1600, Chevy Chase, MD 20815

301-220-1333 |

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